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corio

Clinical softwarefor heart and breath.

Corio is a health technology startup founded by an emergency physician. We build YÜREK, which turns paper ECGs into measurable signals, and SOLUK, a safe place to learn mechanical ventilation.

The paper in this scene comes from a real YÜREK run: the aligned ECG and the trace the model separated from it. The input is an anonymous test image based on PTB-XL.

Two gaps we see at the bedside every day.

Heart

In the emergency department an ECG often stays on paper or in a phone photo. It can't be archived, set beside the last one, or measured.

Breath

Ventilator settings are still learned mostly at the bedside. There is no safe place to see what a setting does to the lung.

Corio builds software for both gaps: first a working tool, then the research that shows its limits.

YÜREK: From a paper ECG to a measurable signal.

YÜREK takes a photo or scan of an ECG printout, flattens the page, separates the trace from the grid and turns all 12 leads into a digital signal in millivolts. The result can be archived, compared and measured.

Research prototype. Not validated for clinical use.

An ECG's path through the pipeline

  1. 1

    Image

    A phone photo or a scanner output. The page can be tilted, shaded or creased.

  2. 2

    Alignment and layout

    The page is flattened; 3×4+1R and 6×2+1R layouts are recognised and each lead is placed.

  3. 3

    Trace separation

    A segmentation model scores every pixel's probability of belonging to the trace; grid and labels fall away.

  4. 4

    Calibrated signal

    Scale is read from the millimetre grid; 12 leads become millivolt values at 500 Hz.

  5. 5

    Measurement and report

    Heart rate, PR, QRS, QT/QTc and rhythm are computed; the structured result can become a PDF report.

Separating the trace from the page

Move the slider: the aligned paper on the left, the model's trace probability map in the same coordinates on the right. Both are real output from the same run.

Aligned paperTrace probability

Look closely at the signal

These drawings are not images: they are redrawn in your browser from the numeric values YÜREK exported. Pick a lead and move across the trace.

II

Move your pointer or finger along the trace

Time
—ms
Amplitude
—mV
Range
—mV
Lead

Each lead shows its 2.5-second segment from the paper (500 Hz, 1,250 samples). Values come from a test image and carry no diagnostic interpretation.

SOLUK: Learn the ventilator before you reach the bedside.

SOLUK is a physiology-based mechanical ventilation training simulator. Learners change settings on a synthetic patient, watch how pressure, flow and volume respond, and predict, observe and reflect in guided lessons.

In development.

Live simulation

This panel runs SOLUK's own simulation engine in your browser. Pick a case, change the settings and wait a few breaths.

Pressure cmH₂OFlow L/minVolume mL
Peak pressure
—cmH₂O
Mean pressure
—cmH₂O
Exhaled VT
—mL
Total rate
—/min
Minute ventilation
—L/min
SpO₂
—%

Synthetic adult patient, volume-controlled mode. Values are educational model output, not measured patient data or treatment advice.

SOLUK's bedside screen: ventilator panel, waveforms, pressure-volume and flow-volume loops, patient assessment and interventions. Synthetic case, Turkish interface.
SOLUK's bedside screen: ventilator panel, waveforms, pressure-volume and flow-volume loops, patient assessment and interventions. Synthetic case, Turkish interface.

The application itself

  • 12 synthetic adult cases

    From baseline mechanics to ARDS, asthma, COPD, pneumothorax and tube displacement.

  • VCV, PCV and PSV

    Volume, flow, rate, PEEP, oxygen and trigger settings, as on a real ventilator.

  • Waveforms and loops

    Pressure, flow and volume over time, with pressure-volume and flow-volume loops.

  • Manoeuvres and blood gas

    Inspiratory and expiratory holds, blood gas samples and trends.

  • Guided lessons

    From first principles to advanced: predict, then observe, then reflect.

  • Built in Turkish

    Designed for physicians in Türkiye, in their own language.

Where we come from, where we are going

  1. March 2026Done

    YÜREK begins

    First version of the paper ECG digitisation pipeline.

  2. September 2026Done

    SOLUK runs

    Physiology-based simulation engine and bedside interface.

  3. October 2026Now

    TÜSEB full application stage

    Both projects passed TÜSEB 2026-B2 preliminary review; the full application is in progress. This is not a funding decision.

  4. NextPlanned

    Validation and pilot

    Ethics-approved validation studies and pilot use with clinicians.

Questions from the clinic, software tested in the clinic.

Zülküf Sergen Ünlü, MD

Founder. Emergency medicine specialist, Mersin.

Founded Corio to turn two questions from daily emergency department work into software. Research interests: AI-assisted triage, ECG analysis and AI in emergency medicine.

How we work

  • A working tool first

    Running software, not slides. Every image on this page is real product output.

  • Say the limits out loud

    We don't present anything unvalidated as validated. A research prototype is called a research prototype.

  • Patient data stays protected

    Development and demos use anonymous or synthetic data. Privacy law is part of the design.

Let's work together.

We are looking for people to build and test YÜREK and SOLUK with us.

  • Clinicians

    Pilot use, feedback and teaching scenarios.

  • Researchers

    Data, validation studies and joint publications.

  • Investors and institutions

    Productisation, support programmes and partnerships.